M'zaka zaposachedwapa, malo osambiramo madzi ozizira—nthawi zina amatchedwa malo ozizira osambiramo kapena malo osambiramo ayezi—asanduka kuchoka pa malo a othamanga apamwamba kupita ku machitidwe odziwika bwino azaumoyo. Umboni wochulukirachulukira wa sayansi kuchokera ku kafukufuku wapadziko lonse komanso wapadziko lonse lapansi ukusonyeza kuti kusamba madzi ozizira nthawi zonse kungathandize kulimbitsa chitetezo chamthupi ndikuwonjezera mphamvu ya thupi.
Kuyankha kwa thupi kumayamba ndi kutentha thupi. Thupi likamizidwa mwadzidzidzi m'madzi ozizira, mitsempha yamagazi imachepa ndipo kuyenda kwa magazi kumayendetsedwa kwakanthawi kuti kuteteze ziwalo zofunika. Mukatuluka m'malo ozizira, mitsempha yamagazi imatuluka, zomwe zimapangitsa kuti magazi aziyenda bwino komanso kuti munthu ayambe kuchira. Kafukufuku akusonyeza kuti njirayi ingayambitse kupanga maselo ena a chitetezo chamthupi, monga ma lymphocyte ndi maselo achilengedwe opha, omwe ndi ofunikira poteteza matenda.
Kuphatikiza apo, kumiza m'madzi ozizira kumakhulupirira kuti kumathandizira dongosolo lamanjenje lodziyimira palokha, zomwe zimawonjezera kuchuluka kwa norepinephrine - mahomoni omwe amagwirizanitsidwa ndi kukhala maso komanso zotsatira zotsutsana ndi kutupa. Kafukufuku wochitidwa ku Europe wasonyeza kuti anthu omwe amasamba m'madzi ozizira nthawi zonse amatha kukhala ndi matenda ochepa a m'mapapo apamwamba poyerekeza ndi omwe sasamba. Ngakhale zotsatira zake zimasiyana ndipo pakufunika maphunziro akuluakulu, izi zikusonyeza kuti chitetezo chamthupi chimatha kupirira.
Kuchokera pamalingaliro ambiri, kuzizira kungathandizenso thupi kuzolowera kupsinjika bwino. Mwa kuyesetsa kugwiritsa ntchito njira yowongolera kutentha, anthu pang'onopang'ono amakulitsa kulolera, zomwe zingathandize kukonza kasamalidwe ka kupsinjika m'moyo watsiku ndi tsiku. Kulimba mtima kumeneku kumaonedwa ngati chowonjezera chamtengo wapatali pa njira zachikhalidwe zosungira thanzi, monga kudya zakudya zoyenera komanso kuchita masewera olimbitsa thupi nthawi zonse.
Komabe, ndikofunikira kuyamba kusamba m'madzi ozizira mosamala. Kumiza mwadzidzidzi kapena kwa nthawi yayitali kungayambitse mavuto, makamaka kwa anthu omwe ali ndi matenda a mtima. Akatswiri amalimbikitsa kuyamba ndi nthawi yochepa—nthawi zambiri yosakwana mphindi ziwiri—ndipo pang'onopang'ono kuwonjezera kuwonekera pamene kulekerera kukukula. Malangizo a akatswiri ndi abwino kwa oyamba kumene.
Pomaliza, kusamba m'madzi ozizira ndi njira yabwino komanso yothandiza kwambiri yowonjezerera mphamvu ya chitetezo chamthupi komanso kulimba mtima. Mwa kulimbikitsa kutentha kwa thupi, kuthandizira mphamvu ya chitetezo chamthupi, komanso kulimbikitsa kusintha kwa kupsinjika, amapereka chithandizo chokwanira ku machitidwe amakono a thanzi. Ngakhale kuti salowa m'malo mwa chithandizo chamankhwala kapena machitidwe amoyo wathanzi, atha kukhala chida chofunikira kwambiri pakufunafuna thanzi lamphamvu komanso kukana matenda.